Research Interests

- Solid state organic chemistry
- Powder diffraction
- Crystal engineering
- Hydrogen bonding
- Polymorphism
- Pharmaceuticals
- Crystal structure prediction
- Monte Carlo techniques
- Evolutionary algorithms
- Differential Evolution
- Cultural Evolution

Recent work on the development of a cultural differential evolution hybrid method and its application to crystal structure determination from powder diffraction data has been featured as a Hot Paper in Chem. Comm., a Research Highlight in Nature, as articles in Chemical Science, Chemistry World and on www.spectroscopynow.com and as a news item in the Materials Research Society Bulletin.

For more details follow the links below:

• Research Interests
• Publications

Career

2000
Royal Society University Research Fellow (University of Birmingham)

1998-1999
Royal Society University Research Fellow (University of St.Andrews)

1997 :
Postdoctoral Research Fellow (University of Glasgow)

1995-1996
Postdoctoral Research Fellow (University College London)

1992-1995
PhD (University of St.Andrews)

1989-1992
BSc First Class (Hons) in Chemistry and Mathematics (University of St.Andrews)

Selected Recent Publications

Combined optimization using cultural and differential evolution: application to crystal structure solution from powder diffraction data. S. Chong & M. Tremayne. Chem. Comm., 4078, (2006).

Molecular versus crystal symmetry in tri-substituted triazine, benzene and isocyanurate derivatives. S. Chong, C. C. Seaton, B. M. Kariuki & M. Tremayne. Acta Cryst., B62, 864, (2006).

Biologically mediated resorption of brushite cement in vitro. L. M. Grover, U. Gbureck, A. J. Wright, M. Tremayne & J. E. Barralet. Biomaterials, 27, 2178, (2006).

The impact of powder diffraction on the structural study of organic materials. M. Tremayne. Phil. Trans. R. Soc. Lond., Series A: Chemistry & Life Sciences Triennial Issue, 362, 2691, (2004).

Characterisation of complicated new polymorphs of chlorothalonil by X-ray diffraction and computer crystal structure prediction. M. Tremayne, L. Grice, J. C. Pyatt, C. C. Seaton , B. M. Kariuki, H. Y. Tsui, S. L. Price & J. C. Cherryman. J. Am. Chem. Soc., 126, 7071, (2004).

Structures of three substituted arenesulfonamides from X-ray powder diffraction data using the differential evolution technique. M. Tremayne, C. C. Seaton & C. Glidewell. Acta Cryst., B58, 823, (2002).

Differential evolution: Crystal structure determination of a triclinic polymorph of adipamide from powder diffraction data. C. C. Seaton & M. Tremayne. Chem. Commun., 880, (2002).

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